Operationally simple hydrotrifluoromethylation of alkenes with sodium triflinate enabled by Ir photoredox catalysis

Operationally simple hydrotrifluoromethylation of alkenes with sodium triflinate enabled by Ir photoredox catalysis

Lei Zhu,*a Lian-Sheng Wang,a Bojie Li,a Boqiao Fu,a Cheng-Pan Zhang*b and Wei Lia
Chem. Commun., 2016, 52, 6371.



We report herein a single component Ir photoredox catalyst which
is capable of catalyzing the hydrotrifluoromethylation of terminal
alkenes and Michael acceptors with sodium triflinate (Langlois
reagent) in methanol under irradiation at room temperature. Various
synthetically useful functional groups, including ester, amide, ether,
aldehyde, sulfone, ketone and aryl boronate, are well tolerated in
this reaction.